Without knowing why the Unna boots are being applied, it is hard to answer.
If you are doing a debridement, it is included with the procedure, they are inclusive to the procedure. The Pub-100 Chapter 4, section G states that debridement codes (11042-11047, 97597) should not be reported with codes 29580, 29581 for the same anatomic area.
Are you actually doing a Unna boot application or a 4-layer dressing? I only ask this as I recently read a Medicare article stating if you are doing a 4-layer dressing use the Unna Boot CPT code 29580 with modifier 22 and include a copy of the procedure report that describes the unusual procedure performed. Article A25749.